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Daigen Xu Selected Research

RN486

9/2013Suppression of glomerulonephritis in lupus-prone NZB × NZW mice by RN486, a selective inhibitor of Bruton's tyrosine kinase.
4/2012RN486, a selective Bruton's tyrosine kinase inhibitor, abrogates immune hypersensitivity responses and arthritis in rodents.

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Daigen Xu Research Topics

Disease

8Arthritis (Polyarthritis)
03/2016 - 12/2006
6Inflammation (Inflammations)
10/2013 - 12/2006
5Pain (Aches)
02/2011 - 12/2006
5Hyperalgesia
10/2009 - 12/2006
4Autoimmune Diseases (Autoimmune Disease)
01/2019 - 10/2013
4Rheumatoid Arthritis
03/2014 - 05/2008
3Neoplasms (Cancer)
01/2019 - 05/2008
2Nephritis
03/2016 - 09/2013
2Experimental Arthritis
04/2012 - 12/2006
1Fibrosis (Cirrhosis)
01/2020
1Asthma (Bronchial Asthma)
03/2014
1Disease Progression
09/2013
1Glomerulonephritis
09/2013
1Hypertension (High Blood Pressure)
08/2012
1Immune Complex Diseases (Immune Complex Disease)
04/2012
1Hypersensitivity (Allergy)
04/2012
1Arthralgia (Joint Pain)
05/2008
1Colorectal Neoplasms (Colorectal Cancer)
05/2008
1Colonic Neoplasms (Colon Cancer)
05/2008
1Intestinal Neoplasms (Intestinal Cancer)
05/2008
1Synovitis
05/2008
1Osteoarthritis
05/2008
1Edema (Dropsy)
04/2007
1Brain Injuries (Brain Injury)
08/2002
1Ischemia
03/2002

Drug/Important Bio-Agent (IBA)

4Agammaglobulinaemia Tyrosine KinaseIBA
01/2019 - 04/2012
4ProstaglandinsIBA
09/2008 - 05/2008
4Prostaglandins EIBA
09/2008 - 12/2006
4Cyclooxygenase 2 (Cyclooxygenase-2)IBA
05/2008 - 12/2006
3Analgesics (Analgesic Drugs)IBA
10/2009 - 12/2007
3Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA
05/2008 - 12/2006
2AutoantibodiesIBA
03/2016 - 05/2008
2Syk KinaseIBA
03/2014 - 10/2013
2RN486IBA
09/2013 - 04/2012
2quinolineIBA
02/2011 - 03/2008
2Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
09/2008 - 12/2006
2Prostaglandin-E SynthasesIBA
09/2008 - 05/2008
23- (3,4- difluorophenyl)- 4- (4- (methylsulfonyl)phenyl)- 2(5H)- furanoneIBA
05/2008 - 04/2007
2Diclofenac (SR 38)FDA LinkGeneric
05/2008 - 12/2006
1Praziquantel (Biltricide)FDA Link
01/2020
1pristane (pristan)IBA
03/2016
1Fc Receptors (Fc Receptor)IBA
03/2016
16- (2- aminocyclohexylamino)- 4- (5,6- dimethylpyridin- 2- ylamino)pyridazine- 3- carboxylic acid amideIBA
10/2013
1Angiotensin IIBA
08/2012
1AngiotensinogenIBA
08/2012
1EnzymesIBA
08/2012
1Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
08/2012
1ReninIBA
08/2012
1Methotrexate (Mexate)FDA LinkGeneric
04/2012
1naphthaleneIBA
02/2011
1Benzoic Acid (Potassium Benzoate)FDA Link
06/2010
1AntipyreticsIBA
09/2008
1LipopolysaccharidesIBA
09/2008
1LipidsIBA
05/2008
1acetamideIBA
05/2008
1Dinoprostone (PGE2)FDA Link
05/2008
1Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
05/2008
1CarcinogensIBA
05/2008
1Cyclooxygenase 1IBA
05/2008
1Protein Isoforms (Isoforms)IBA
05/2008
1CollagenIBA
05/2008
1CarrageenanIBA
04/2007
1N-(2-naphthalene)sulfonyl-DL-tryptophan (A 91)IBA
12/2006
1Epoprostenol (Prostacyclin)FDA LinkGeneric
12/2006
1benzamideIBA
12/2006
1CaspasesIBA
08/2002
1CalpainIBA
08/2002
1Peptides (Polypeptides)IBA
08/2002
1Caspase 3 (Caspase-3)IBA
08/2002
1Uridine Triphosphate (UTP)IBA
03/2002

Therapy/Procedure

1Oral Administration
10/2013
1Therapeutics
10/2013
1Chemoprevention
05/2008